Hund-Rudy Model
for one canine ventricular cell
This model is used to simulate the activation of canine ventricular cells using the
model of Hund and Rudy.
To use the applet, click the Start button to initiate
the simulation and the Reset button to return
the parameters to their initial values. Check the box for each
variable to plot it in the window.
The final action potential duration (APD)
and diastolic interval (DI) are calculated automatically.
Press the Plot Currents button to view the individual transmembrane currents.
N(s1's) indicates the number of stimuli given at the
cycle length indicated by S1 (bcl).
S2 indicates the timing of the last stimulus.
Things to try:
Uncheck the Voltage box and check the boxes for some of the other variables.
Change N(S1's), S1, and S2 to calculate points on APD restitution curves.
After pressing the Plot Currents button, check the Ascii data box
to obtain the voltage signal as a function of time.
(Note that the larger the signal, the longer
it takes for the window to appear.)
Hund T, Rudy Y. (2004) Circulation 110, 3168-3174.