Noble Model for Purkinje Cells

One-dimensional Cable/Ring

This applet simulates the Noble model in a 1D cable or 1D ring of any length between 0.5 cm and 27.5 cm. Initiation by a stimulus, propagation, and complex dynamics such as discordant alternans can be studied.
To learn more about the model in single cell, use the Noble single cell applet.

Note: since the Noble model is auto-oscillatory with its original parameter settings, here gna is decreased from its original value of 0.14 to 0.12 to make the system excitable.


Suggested Experiments:

The model can be found in the following reference: D Noble, J Physiol 1962; 160: 317-352.